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Anti-USP20 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | USP20 rabbit polyclonal antibody |
Gene Name: | Ubiquitin carboxyl-terminal hydrolase 20 |
Synonyms: | Deubiquitinating enzyme 20, Ubiquitin thioesterase 20, Ubiquitin-specific-processing protease 20, VHL-interacting deubiquitinating enzyme 2, Usp20, Kiaa1003, Vdu2 |
Immunogen: | Recombinant protein corresponding to Mouse USP20 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 102 kDa |
Observed MW. | 120 kDa |
Uniprot ID: | Q9Y2K6 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 1000-1: 2000 | HeLa |
Background
USP20(ubiquitin carboxyl-terminal hydrolase 20) is also named as KIAA1003, LSFR3A, VDU2 and belongs to the peptidase C19 family and the USP20/USP33 subfamily. It can specifically deubiquitinate and stabilize HIF1A and, therefore, increase expression of HIF-1alpha targeted genes, such as vascular endothelial growth factor (VEGF). It also plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2.
Images
 | Western blot analysis of USP20 (GB112667) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |