Reactivity: | Human, Mouse, Rat |
Applications: | WB, IHC, ELISA |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Polyclonal antibody |
Gene Name: | vasoactive intestinal peptide |
Gene Symbol: | VIP |
Synonyms: | PHM27; VIP |
Gene ID: | 7432 |
UniProt ID: | P01282 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-170 of human VIP (NP_003372.1). |
Dilution: | WB 1:500-1:2000; IHC 1:50-1:200 |
Purification Method: | Affinity purification |
Concentration: | 0.61 mg/ml |
Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Documents: | Manual-VIP antibody |
Background
The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
Images
![]() | Western blot analysis of lysates from rat spinal cord, using VIP Rabbit pAb (A12531) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
![]() | Immunohistochemistry analysis of paraffin-embedded Human esophageal using VIP Rabbit pAb (A12531) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining. |
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