Reactivity: | Human, Rat |
Applications: | WB, ELISA |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Polyclonal antibody |
Gene Name: | regulating synaptic membrane exocytosis 2 |
Gene Symbol: | RIMS2 |
Synonyms: | OBOE; RIM2; CRSDS; RAB3IP3; RIMS2 |
Gene ID: | 9699 |
UniProt ID: | Q9UQ26 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human RIMS2 (NP_055492.3). |
Dilution: | WB 1:500-1:2000 |
Purification Method: | Affinity purification |
Concentration: | 2.35 mg/ml |
Buffer: | Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Documents: | Manual-RIMS2 antibody |
Background
The protein encoded by this gene is a presynaptic protein that interacts with RAB3, a protein important for normal neurotransmitter release. The encoded protein can also bind several other synaptic proteins, including UNC-13 homolog B, ELKS/Rab6-interacting/CAST family member 1, and synaptotagmin 1. This protein is involved in synaptic membrane exocytosis. Polymorphisms in this gene have been associated with degenerative lumbar scoliosis.
Images
![]() | Western blot analysis of various lysates using RIMS2 Rabbit pAb (A14990) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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