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Anti-ROR alpha/RORA Mouse mAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Nuclear receptor ROR-alpha |
Synonyms: | Nuclear receptor RZR-alpha, Nuclear receptor subfamily 1 group F member 1, RAR-related orphan receptor A, Retinoid-related orphan receptor-alpha, Rora, Nr1f1, Rzra |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ROR alpha/RORA |
Uniprot ID: | P51448 |
Isotype: | IgG2a,κ |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC/IF | Human, Mouse, Rat | 1: 900-1: 1800 | brain, heart, kidney |
Background
RORA is a steroid hormone receptor and has been implicated in the pathology of circadian rhythms, bone growth, angiogenesis, development of cones, cellular metabolism and a mediator in the immune and lipid metabolism pathways . It binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence, which binds to the consensus sequence 5'-[AT][TA]A[AT][CGT]TAGGTCA-3'.
Images
| Immunohistochemistry analysis of paraffin-embedded human kidney cancer using RORA (GB121300) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded mouse brain using RORA (GB121300) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded rat brain using RORA (GB121300) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded mouse heart using RORA (GB121300) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded rat heart using RORA (GB121300) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |