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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RPL7 rabbit polyclonal antibody |
Gene Name: | 60S ribosomal protein L7 |
Synonyms: | Rpl7, humL7 1, Ribosomal protein L7, Surf 3, L7, Rpl7a |
Immunogen: | Recombinant protein corresponding to Mouse RPL7 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 31 kDa |
Observed MW. | 31 kDa |
Uniprot ID: | P18124, P14148, P05426 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | spleen, kidney, liver |
Background
The mammalian ribosome comprises 79 ribosomal proteins and four rRNAs, which combine in equimolar ratios to form the small (40S) and large (60S) subunits. Ribosome proteins are a direct and critical target of the PI3K pathway in promoting growth. RPL7 binds to G-rich structures in 28S rRNA, and plays a regulatory role in the translation apparatus, inhibits cell-free translation of mRNAs. In addition, RPL7 is suggested to have a role as an integral part of natural freeze tolerance. Besides, RPL7 is responsible for its normal ribosome functions including the nuclear targeting, ribosome assembly and translation.
Images
| Western blot analysis of Rpl7 (GB111756) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |