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| Reactivity: | H,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RST rabbit polyclonal antibody |
Gene Name: | Solute carrier family 22 member 12 |
Synonyms: | Renal-specific transporter, RST, Urate anion exchanger 1, Slc22a12, Urat1 |
Immunogen: | Recombinant protein corresponding to Mouse RST |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | Q96S37, Q8CFZ5, Q3ZAV1 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Rat | 1: 700-1: 2100 | kidney |
Background
SLC22A12, also known as Human urate anion exchanger (URAT1), is a urate transporter located in the proximal tubules of human kidney and responsible for urate reabsorption. Defects in gene encoding URAT1 cause hypouricemia renal type 1 (RHUC1). This antibody recognizes the native and glycosylated URAT1 between 65 and 70 kDa as well as the truncated 40kDa protein.
Images
| Immunohistochemistry of paraffin embedded human kidney using SLC22A12 (GB111847) at dilution of 1:2100 (300x lens) |
| Immunofluorescence of paraffin embedded rat kidney using SLC22A12 (GB111847) at dilution of 1:2000 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |