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Anti-RTN3/HAP Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Reticulon-3 |
Synonyms: | ASYIP, HAP, NSP like protein 2, NSP like protein II, NSPL2, NSPLII, reticulon 3, RTN3, RTN3 A1 |
Immunogen: | Recombinant protein corresponding to Mouse RTN3 |
Uniprot ID: | Q9ES97 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Endoplasmic reticulum, Golgi apparatus, Membrane |
Product Usage Information
IHC/IF | Mouse | 1: 1000-1: 2000 | brain, cerebellum |
Background
May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress (By similarity). Induces the formation of endoplasmic reticulum tubules.
Images
| Immunohistochemistry analysis of paraffin embedded mouse Brain using RTN3 (GB114482) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse cerebellum using RTN3 (GB114482) at dilution of 1: 1000 |
| Immunofluorescence analysis of paraffin embedded mouse cerebellum using RTN3 (GB114482) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |