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| Reactivity: | Monkey |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | Unconjugated |
| Gene Symbol: | immunoglobulin epsilon heavy chain |
| Synonyms: | IgE; IGHE |
| Clone ID: | 4R2F4 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 99-429 of Monkey IgE(EHH62331.1). |
| Dilution: | FC,1:500 - 1:1000 |
| Concentration: | 1 mg/ml |
| Buffer: | PBS with 0.05% proclin300,0.05% BSA,50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual- |
Background
IgE is the class of antibodies produced in the lungs, skin, and mucous membranes. It may protect against parasite invasion, but it is a major factor in allergic reactions. The antigen-specific IgE interacts with mast cells and eosinophils, triggers the release of histamine, leukotrienes and other substances that lead to the itching, sneezing and congestion of allergies - and the life threatening respiratory distress of asthma and anaphylactic shock.
Images
 | Flow cytometry: 1×10^6 Monkey PBMC were surface-stained with Rabbit IgG isotype control (AC042,2 μg/mL,left) or Rabbit anti-Monkey IgE mAb (A27383,2 μg/mL,right), followed by Alexa Fluor® 488 conjugated goat anti-rabbit pAb staining. |
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