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| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | S6K1 rabbit polyclonal |
Gene Name: | Ribosomal protein S6 kinase beta-1 |
Synonyms: | S6K-beta-1, S6K1, P70S6K1, S6K, Ribosomal protein S6 kinase I, P70 S6 kinase alpha, Rps6kb1, 70 kDa ribosomal protein S6 kinase 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse S6K1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1: 500-1: 1000 | liver, brain |
IF | Human, Mouse, Rat | 1: 500-1: 1000 | liver, brain |
Background
Ribosomal protein S6 kinase beta-1 (S6K1), also known as p70S6 kinase (p70S6K, p70-S6K), is an enzyme(specifically, a protein kinase) that in humans is encoded by the RPS6KB1 gene. It is a serine/threonine kinase that acts downstream of PIP3 and phosphoinositide-dependent kinase-1 in the PI3 kinase pathway. As the name suggests, its target substrate is the S6 ribosomal protein. Phosphorylation of S6 induces protein synthesis at the ribosome.
Images
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Immunohistochemistry analysis of paraffin-embedded human liver using S6K1 (GB11298A) at dilution of 1: 500 |
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Immunohistochemistry analysis of paraffin-embedded rat liver using S6K1 (GB11298A) at dilution of 1: 500 |
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Immunohistochemistry analysis of paraffin-embedded rat brain using P70S6K1 (GB11298A) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse liver using P70S6K1 (GB11298A) at dilution of 1: 500 |
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Immunohistochemistry analysis of paraffin-embedded mouse brain using P70S6K1 (GB11298A) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |