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| Reactivity: | Human |
| Applications: | IF/IC, ELISA |
| Host Species: | Rabbit |
| Clonality: | Polyclonal antibody |
| Gene Name: | SET domain containing 5 |
| Gene Symbol: | SETD5 |
| Synonyms: | MRD23; SETD5A; SETD5 |
| Gene ID: | 55209 |
| UniProt ID: | Q9C0A6 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 520-740 of human SETD5 (NP_001073986.1). |
| Dilution: | IF/IC 1:50-1:200 |
| Purification Method: | Affinity purification |
| Concentration: | 0.7 mg/ml |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-SETD5 antibody |
Background
This function of this gene has yet to be determined but based on sequence similarity to other SET domain proteins it may function as a histone methyltransferase. Mutations in this gene have been associated with an autosomal dominant form of intellectual disability. Alternative splicing results in multiple transcript variants encoding different isoforms.
Images
 | Immunofluorescence analysis of MCF-7 cells using SETD5 Rabbit pAb (A14140). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining. |
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