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Anti-SLAP2 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SLAP2 rabbit polyclonal antibody |
Gene Name: | Src-like-adapter 2 |
Synonyms: | C20orf156, MARS, SLA2, SLAP2, Src like adaptor 2, Modulator of antigen receptor signaling |
Immunogen: | Recombinant protein corresponding to Mouse SLAP2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Cell membrane |
Uniprot ID: | Q8R4L0 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 750-1: 1500 | tonsil |
Background
Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
Images
| Immunohistochemistry analysis of paraffin embedded human tonsil using SLA2 (GB114100) at dilution of 1: 750 |
| Immunohistochemistry analysis of paraffin embedded human tonsil using SLA2 (GB114100) at dilution of 1: 750 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |