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| Reactivity: | Human, Mouse |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Clonality: | Polyclonal antibody |
| Gene Name: | solute carrier family 4 member 11 |
| Gene Symbol: | SLC4A11 |
| Synonyms: | BTR1; CHED; CDPD1; CHED2; NABC1; dJ794I6.2; SLC4A11 |
| Gene ID: | 83959 |
| UniProt ID: | Q8NBS3 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SLC4A11 (NP_001167560.1). |
| Dilution: | WB 1:1000-1:5000 |
| Purification Method: | Affinity purification |
| Concentration: | 2.05 mg/ml |
| Buffer: | Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-SLC4A11 antibody |
Background
This gene encodes a voltage-regulated, electrogenic sodium-coupled borate cotransporter that is essential for borate homeostasis, cell growth and cell proliferation. Mutations in this gene have been associated with a number of endothelial corneal dystrophies including recessive corneal endothelial dystrophy 2, corneal dystrophy and perceptive deafness, and Fuchs endothelial corneal dystrophy. Multiple transcript variants encoding different isoforms have been described.
Images
 | Western blot analysis of lysates from HepG2 cells, using SLC4A11 Rabbit pAb (A15910) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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