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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SPZ1 rabbit polyclonal antibody |
Gene Name: | Spermatogenic leucine zipper protein 1 |
Synonyms: | BHLH-Zip transcription factor SPZ1, Spermatogenic Zip 1, Spz1, NYD TSP1, PP1C gamma 2, PPP1R148, Protein phosphatase 1, regulatory subunit 148 , Testis specific protein 1 |
Immunogen: | Recombinant protein corresponding to Mouse SPZ1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 43 kDa |
Observed MW. | 43 kDa |
Uniprot ID: | Q99MY0, Q6AXY9 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | brain, kidney, testis |
Background
Spermatogenic leucine zipper protein 1 is a member of the basic helix-loop-helix (bHLH) family of transcription factors which is expressed specifically in the testis and epididymis. Studies show that SPZ1 acts downstream of mitogen-activated protein kinase (MAPK), an extracellular signal-regulated kinase 1/2 to up-regulate cell proliferation and tumorigenesis. Also, through an interaction with proliferating cell nuclear antigen (PCNA) promoter, SPZ1 induced cell proliferation concomitant with an increase in PCNA gene expression.
Images
| Western blot analysis of SPZ1 (GB111749) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |