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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | STAC rabbit polyclonal antibody |
Gene Name: | SH3 and cysteine-rich domain-containing protein |
Synonyms: | Src homology 3 and cysteine-rich domain-containing protein, Stac, Stac1 |
Immunogen: | Recombinant protein corresponding to Mouse STAC |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 44 kDa |
Observed MW. | 44 kDa |
Uniprot ID: | Q99469, P97306 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 3000-1: 6000 | testis |
Background
STAC is a 402 amino acid protein that contains one SH3 (Src homology 3) domain and one cysteine-rich domain (CRD). Expressed in brain, STAC is a neuron-specific protein that localizes to the cytoplasm and, based on the frequent involvement of SH3 and CRD domains in signal transduction, is believed to play a role in neuron-specific signal transduction. In addition, STAC may be involved in protecting cells from apoptosis. Due to its neuron-specific expression and putative role in signal transduction, STAC may be implicated in a variety of hereditary neurological diseases.
Images
 | Western blot analysis of STAC (GB112746) at dilution of 1: 3000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |