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| Reactivity: | Mouse |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Clonality: | Polyclonal antibody |
| Gene Name: | synaptopodin 2 |
| Gene Symbol: | SYNPO2 |
| Synonyms: | SYISL; SYNPO2 |
| Gene ID: | 171024 |
| UniProt ID: | Q9UMS6 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SYNPO2 (NP_597734.2). |
| Dilution: | WB 1:500-1:1000 |
| Purification Method: | Affinity purification |
| Concentration: | 0.27 mg/ml |
| Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-SYNPO2 antibody |
Background
Enables alpha-actinin binding activity and filamin binding activity. Involved in positive regulation of actin filament bundle assembly; positive regulation of cell migration; and regulation of Rho-dependent protein serine/threonine kinase activity. Located in several cellular components, including Z disc; focal adhesion; and stress fiber.
Images
 | Western blot analysis of lysates from mouse skeletal muscle, using SYNPO2 Rabbit pAb (A12881) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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