| Reactivity: | R | 
| Applications: | WB | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Gene Name: | Serine palmitoyltransferase 2  | 
Synonyms:  | KIAA0526, LCB 2, LCB2, LCB2a, Serine palmitoyltransferase 2, SPT 2, SPT2, SPTLC2  | 
Immunogen:  | KLH conjugated Synthetic peptide corresponding to Mouse Serine Palmitoyltransferase  | 
Uniprot ID:  | P97363  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Predicted MW. / Observed MW.  | 63 kDa / 65 kDa  | 
Product Usage Information
WB  | Rat  | 1: 300-1: 500  | colon, liver  | 
Background
Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate (By similarity). Plays an important role in de novo sphyngolipid biosynthesis which is crucial for adipogenesis.
Images
  | Western blot analysis of Serine Palmitoyltransferase (GB114312) at dilution of 1: 500  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |