Reactivity: | H,M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | 5-hydroxytryptamine receptor 3B |
Synonyms: | 5-HT3-B, Serotonin receptor 3B, Htr3b, 5 hydroxytryptamine serotonin receptor 3B, Htr3b, Serotonin gated ion channel subunit |
Immunogen: | Recombinant protein corresponding to Mouse 5HT3B receptor |
Uniprot ID: | Q9JHJ5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 50 kDa / 50-55 kDa |
Product Usage Information
WB | Human, Mouse | 1: 500-1: 1000 | kidney |
Background
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine , a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude.
Images
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Western blot analysis of Prkar2b (GB111373) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |