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Anti-ADCY4 Rabbit pAb (100 μl)
| Reactivity: | M & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ADCY4 rabbit polyclonal antibody |
Gene Name: | Adenylate cyclase type 4 |
Synonyms: | ATP pyrophosphate-lyase 4, Adenylate cyclase type IV, Adenylyl cyclase 4, Adcy4, AC4, Adenylyl cyclase, ATP pyrophosphate lyase |
Immunogen: | Recombinant protein corresponding to Mouse ADCY4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Predicted MW. | 120 kDa |
Observed MW. | 120 kDa |
Uniprot ID: | Q91WF3 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse | 1: 250-1: 500 | stomach, kidney, lung |
IHC/IF | Mouse, Rat | 1: 700-1: 1400 | duodenum, kidney |
Background
The ADCY4 gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants.
Images
| Western blot analysis of ADCY4 (GB112265) at dilution of 1: 250 |
| Immunohistochemistry of paraffin embedded mouse duodenum using ADCY4 (GB112265) at dilution of 1: 700 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse kidney using ADCY4 (GB112265) at dilution of 1: 700 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |