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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ATF1 rabbit polyclonal antibody |
Gene Name: | Cyclic AMP-dependent transcription factor ATF-1 |
Synonyms: | ATF1, EWS-FUS/ATF-1, TREB36, activating transcription factor 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ATF1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 29 kDa |
Observed MW. | 29 kDa |
Uniprot ID: | P18846, P81269 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | colon, brain, kidney |
Background
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation .
Images
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Western blot analysis of ATF1 (GB11288) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |