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| Reactivity: | H & R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | BCMA rabbit polyclonal antibody |
Gene Name: | Tumor necrosis factor receptor superfamily member 17 |
Synonyms: | B-cell maturation protein, CD269, Tnfrsf17, Bcm, Bcma |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse BCMA |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Predicted MW. | 20 kDa |
Observed MW. | 20 kDa |
Uniprot ID: | Q02223 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 250-1: 500 | Raji, K562, Jurkat |
IHC/IF | Rat | 1: 600-1: 1200 | Skeletal muscle, spleen |
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
Images
| Western blot analysis of BCMA (GB112202) at dilution of 1: 250 |
| Immunofluorescence of paraffin embedded rat skeletal muscle using BCMA (GB112202) at dilution of 1: 600 (250x lens) |
| Immunofluorescence of paraffin embedded rat skeletal muscle using BCMA (GB112202) at dilution of 1: 600 (400x lens) |
| Immunofluorescence of paraffin embedded rat spleen using BCMA (GB112202) at dilution of 1: 600 (450x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |