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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Valacyclovir hydrolase |
Synonyms: | BPH RP, BPHL, MCNAA, VACVASE, Valacyclovir hydrolase, Valacyclovirase |
Immunogen: | Recombinant protein corresponding to Mouse BPHL |
Uniprot ID: | Q8R164 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 33 kDa / 32 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 300- 1: 600 | liver, kidney |
Background
Serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovir to acyclovir. May play a role in detoxification processes. It is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol (By similarity).
Images
| Western blot analysis of BPHL (GB114184) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |