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Anti-CKAP4 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CKAP4 rabbit polyclonal antibody |
Gene Name: | Cytoskeleton-associated protein 4 |
Synonyms: | 3-kDa cytoskeleton-linking membrane protein, Climp-63, p63, Ckap4 |
Immunogen: | Recombinant protein corresponding to Mouse CKAP4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Predicted MW. | 64 kDa |
Observed MW. | 64 kDa |
Uniprot ID: | Q07065, Q8BMK4 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, lung, testis |
IHC/IF | Mouse, Rat | 1: 500-1: 3000 | brain, lung |
Background
CKAP4, also named as Climp-63, is a 63 kDa cytoskeleton-linking membrane protein. It is the partner of triadin. CKAP4 is responsible for this association of triads and microtubules. CKAP4 is a substrate of DHHC2, a putative tumor suppressor. CK MNF116 and p63 were useful in identifying squamous cell carcinomas with single cell infiltration. Those results suggested a role of CKAP4/p63 in tumor.
Images
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Western blot analysis of CKAP4 (GB111437) at dilution of 1: 500 |
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Immunohistochemistry of paraffin embedded mouse brain using CKAP4 (GB111437) at dilution of 1: 1000 (300x lens) |
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Immunohistochemistry of paraffin embedded rat lung using CKAP4 (GB111437) at dilution of 1: 500 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using CKAP4 (GB111437) at dilution of 1: 2000 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |