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Anti-Cathepsin B Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Cathepsin B |
Synonyms: | APP secretase, APPS, cathepsin B, Cathepsin B1, CPSB, CTSB |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CTSB |
Uniprot ID: | P10605 |
Isotype: | lgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Product Usage Information
IHC/IF | Human | 1: 100-1: 200 | lung cancer, colon, kidney |
Background
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis.
Images
| Immunohistochemistry analysis of paraffin embedded human kidney using Cathepsin B (GB115596) at dilution of 1: 150 |
| Immunohistochemistry analysis of paraffin embedded human colon using Cathepsin B (GB115596) at dilution of 1: 150 |
| Immunohistochemistry analysis of paraffin embedded human lung cancer using Cathepsin B (GB115596) at dilution of 1: 150 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |