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Anti-DC-SIGNR Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | C-type lectin domain family 4 member M |
Synonyms: | CD209 antigen like protein 1, CD209L, CD209L1, CD299, CLEC4M, DC SIGN related protein, DC SIGN2, DC SIGNR, DCSIGNR, HP10347, L SIGN, LSIGN |
Immunogen: | Recombinant protein corresponding to Human DC-SIGNR |
Uniprot ID: | Q9H2X3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Secreted |
Product Usage Information
IHC/IF | Human | 1: 1500-1: 3000 | liver |
Background
Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates.
Images
| Immunohistochemistry analysis of paraffin embedded human liver using CLEC4M (GB114161) at dilution of 1: 1500 |
| Immunofluorescence analysis of paraffin embedded human liver using CLEC4M (GB114161) at dilution of 1: 1500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |