| Reactivity: | M,R | 
| Applications: | WB | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Gene Name: | DENN domain-containing protein 4C  | 
Synonyms:  | CXX1b, FAM127B, MAR8A, Protein FAM127B, RTL8A, SIRH6  | 
Immunogen:  | Recombinant protein corresponding to Mouse DENND4C  | 
Uniprot ID:  | A6H8H2  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Predicted MW. / Observed MW.  | 211 kDa / 216 kDa  | 
Product Usage Information
WB  | Mouse, Rat  | 1: 500-1: 1000  | liver, liver, thymus, lung  | 
Background
Guanine nucleotide exchange factor (GEF) activating RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin.
Images
  | Western blot analysis of DENND4C (GB114219) at dilution of 1: 1000  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |