| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Deformed epidermal autoregulatory factor 1 homolog |
Synonyms: | DEAF1, NUDR, SPN, Suppressin, ZMYND5 |
Immunogen: | Recombinant protein corresponding to Mouse Deformed Epidermal Autoregulatory Factor 1 |
Uniprot ID: | Q9Z1T5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 60 kDa / 70 kDa |
Product Usage Information
WB | Human, Mouse | 1: 500-1: 1000 | testis |
Background
Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction (By similarity). Regulates epithelial cell proliferation and side-branching in the mammary gland. Required for neural tube closure and skeletal patterning. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes.
Images
| Western blot analysis of DEAF1 (GB114501) at dilution of 1: 1000 |
| Western blot analysis of DEAF1 (GB114501) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |