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Anti-Endofin Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Endofin rabbit polyclonal antibody |
Gene Name: | Zinc finger FYVE domain-containing protein 16 |
Synonyms: | Endofin, Endosomal-associated FYVE domain protein, Zfyve16, Kiaa0305 |
Immunogen: | Recombinant protein corresponding to Mouse Endofin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 167 kDa |
Observed MW. | 167 kDa |
Uniprot ID: | Q7Z3T8 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | HeLa, MCF-7 |
Background
Endofin (also known as ZFYVE16) is an endosomal FYVE domain protein implicated in regulating membrane trafficking. Endofin has been shown to localize to early endosomes. It co-localizes with SARA but does not associate with it or Smad2 and does not behave like SARA in affecting TGF-signaling. Northern blot analysis showed ZFYVE16 was widely expressed with high levels in kidney, placenta and lung. Overexpression of Endofin causes endosome aggregation.
Images
 | Western blot analysis of ZFYVE16 (GB112938) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |