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Anti-Fibromodulin Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Fibromodulin rabbit polyclonal |
Gene Name: | Fibromodulin |
Synonyms: | FM, FMOD, KSPG fibromodulin, SLRR2E, Collagen binding 59 kDa protein, Keratan sulfate proteoglycan fibromodulin, Fibromodulin precursor |
Immunogen: | Recombinant protein corresponding to Mouse Fibromodulin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 43 kDa |
Observed MW. | 45 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | HepG2, A431, CaCO2 |
Background
Fibromodulin (FMOD), an extracellular matrix protein, belongs to the small leucine-rich proteoglycan family. Fibromodulin is a collagen-binding protein present in many types of connective tissues, e.g. cartilage, tendon, skin, sclera and cornea . It is involved in fibrillogenesis, cell adhesion, and cytokine activity modulation . Fibromodulin may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. The calculated molecular mass of fibromodulin is 43 kDa, extracellular fibromodulin appears as one single band of 59 kDa due to glycosylation.
Images
 | Western blot analysis of FMOD (GB113515) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |