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Anti-GADD45A Rabbit pAb (100 μl)
| Reactivity: | R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | GADD45A rabbit polyclonal antibody |
Gene Name: | Growth arrest and DNA damage-inducible protein GADD45 alpha |
Synonyms: | GADD45A, DDIT1, GADD45, growth arrest and DNA damage inducible alpha |
Immunogen: | Recombinant protein corresponding to Mouse GADD45A |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Rat | 1: 500-1: 2000 | colon, heart, lung, testis |
Background
Growth arrest and DNA-damage-inducible protein GADD45 alpha is a protein that in humans is encoded by the GADD45A gene. This gene is a member of a group of genes, the GADD45 genes, whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents (mutagens). The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase.
Images
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Immunohistochemistry of paraffin embedded rat colon using GADD45α (GB11576) at dilution of 1:1500 (400x lens) |
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Immunohistochemistry of paraffin embedded rat heart using GADD45α (GB11576) at dilution of 1:2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat lung using GADD45α (GB11576) at dilution of 1:1500 (400x lens) |
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Immunohistochemistry of paraffin embedded rat testis using GADD45α (GB11576) at dilution of 1:1500 (400x lens) |
Storage
| Storage |
Store at -20°C for one year. Avoid repeated freeze/thaw cycles |
| Storage Buffer |
PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol. |