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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | GAMT rabbit polyclonal antibody |
Gene Name: | Guanidinoacetate N-methyltransferase |
Synonyms: | Gamt, TP53I2, PIG2, CCDS2, Epididymis secretory protein Li 20 |
Immunogen: | Recombinant protein corresponding to Mouse GAMT |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 26 kDa |
Observed MW. | 26 kDa |
Uniprot ID: | O35969, P10868 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | testis, ovary, liver |
Background
GAMT converts the latter to creatine with S-adenosylmethionine as the methyl donor. GAMT was induced in human and mouse cells in response to genotoxic and metabolic stress. GAMT was required for p53-dependent upregulation of creatine biosynthesis, fatty acid oxidation, and apoptosis in response to glucose deprivation.
Images
 | Western blot analysis of GAMT (GB111510) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |