| Reactivity: | R | 
| Applications: | IHC/IF | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Gene Name: | Erythroid transcription factor  | 
Synonyms:  | ERYF1, Erythroid transcription factor, GATA 1, GATA binding factor 1, GATA1, GF 1, GF1, NF E1 DNA binding protein  | 
Immunogen:  | KLH conjugated Synthetic peptide corresponding to Mouse GATA 1  | 
Uniprot ID:  | P17679  | 
Isotype:  | lgG  | 
Purity:  | Affinity purification  | 
Subcellular location:  | Nucleus  | 
Product Usage Information
IHC/IF  | Rat  | 1: 150-1: 300  | testis, liver, bone  | 
Background
Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS.
Images
  | Immunohistochemistry analysis of paraffin embedded rat bone using GATA1 (GB115594) at dilution of 1: 150 | 
  | Immunohistochemistry analysis of paraffin embedded rat liver using GATA1 (GB115594) at dilution of 1: 150 | 
  | Immunohistochemistry analysis of paraffin embedded rat testis using GATA1 (GB115594) at dilution of 1: 150 | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |