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| Reactivity: | M,R & H,M,R |
| Applications: | WB, IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Glial fibrillary acidic protein |
| Gene Symbol: | GFAP |
| Synonyms: | ALXDRD |
| Immunogen: | KLH conjugated Synthetic peptide corresponding to Human GFAP |
| Gene ID: | 2670 |
| Uniprot ID: | P14136 |
| Isotype: | IgG2b,κ |
| Purity: | Affinity purification |
| Subcellular location: | Cytoplasm |
| Documents: | Manual-GFAP Antibody |
Product Usage Information
WB |
Mouse, Rat |
1: 500-1: 1000 |
brain, cerebellum, cerebral cortex, hippocampus |
IHC/IF |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain, glioma, oligodendroglioma |
Background
The gene GFAP encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Images
|
Western blot analysis of GFAP (GB12090) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin embedded rat Brain using GFAP (GB12090) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin embedded mouse Brain using GFAP (GB12090) at dilution of 1: 1000 |
|
Immunohistochemistry analysis of paraffin embedded human glioma using GFAP (GB12090) at dilution of 1: 1000 |
|
Immunohistochemistry analysis of paraffin embedded human oligodendroglioma using GFAP (GB12090) at dilution of 1: 500 |
Storage
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
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