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Anti-IL-17A Receptor Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IL-17A Receptor rabbit polyclonal antibody |
Gene Name: | Interleukin-17 receptor A |
Synonyms: | IL17RA, CANDF5, CD217, CDw217, IL-17RA, IL17R, hIL-17R, interleukin 17 receptor A, IMD51 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human IL-17A Receptor |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 96 kDa |
Observed MW. | 110 kDa |
Uniprot ID: | Q96F46 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | Jurkat, HTP-1, A20 |
Background
Interleukin 17 receptor A, also known as IL17RA and CDw217 (cluster of differentiation w217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.
Images
 |
Western blot analysis of IL-17Ra (GB11586) at dilution of 1: 500 |
Storage
| Storage |
Store at -20°C for one year. Avoid repeated freeze/thaw cycles |
| Storage Buffer |
PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol. |