| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IL-1RA rabbit polyclonal antibody |
Gene Name: | Interleukin-1 receptor antagonist protein |
Synonyms: | IL-1RN, IL-1ra, IRAP, IL1 inhibitor, DIRA, IL1RA, IL1RN, MVCD4, Type II interleukin 1 receptor antagonist |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse IL-1RA |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 20 kDa |
Observed MW. | 20 kDa |
Uniprot ID: | P25085, P25086 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | pancreas |
Background
IL1RA is a member of the Interleukin 1 cytokine family. This protein inhibits the activities of Interleukin 1, alpha (IL1A) and Interleukin 1, beta (IL1B), and modulates a variety of Interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Images
| Western blot analysis of IL1RA(GB112096) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |