| Reactivity: | M,R & M,R | 
| Applications: | WB & IHC/IF | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Full Name: | ITLN1 rabbit polyclonal antibody  | 
Gene Name:  | Intelectin-1a  | 
Synonyms:  | Endothelial lectin HL 1, Galactofuranose binding lectin, hIntL, HL 1, HL1, Intelectin 1, INTL, ITLN, ITLN 1, ITLN1, LFR, omentin  | 
Immunogen:  | Recombinant protein corresponding to Mouse ITLN1  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Subcellular location:  | Cell membrane, Secreted  | 
Predicted MW.  | 35 kDa  | 
Observed MW.  | 37 kDa  | 
Uniprot ID:  | O88310  | 
Product Usage Information
Applications  | Species  | Dilution  | Positive Sample  | 
WB  | Mouse, Rat  | 1: 1000-1: 2000  | colon  | 
IHC/IF  | Mouse, Rat  | 1: 500-1: 1500  | jejunum, colon  | 
Background
Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner . Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris. Does not bind mammalian glycans. Probably plays a role in the defense system against microorganisms.
Images
  | Western blot analysis of ITLN1 (GB114115) at dilution of 1: 1000  | 
  | Immunohistochemistry analysis of paraffin embedded mouse jejunum using ITLN1 (GB114115) at dilution of 1: 1000  | 
  | Immunohistochemistry analysis of paraffin embedded rat colon using ITLN1 (GB114115) at dilution of 1: 1000  | 
  | Immunofluorescence of paraffin embedded rat jejunum using ITLN1 (GB114115) at dilution of 1: 1000  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |