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Anti-Insulin Receptor beta Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Insulin Receptor beta rabbit polyclonal |
Gene Name: | Insulin receptor |
Synonyms: | CD220, HHF5, INSR, IR, Insulin receptor subunit beta |
Immunogen: | KLH conjugated Synthetic peptide corresponding to mouse Insulin Receptor beta |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 156 kDa |
Observed MW. | 95/220 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | liver, fat, skeletal muscle |
Background
The biological effects of INS are mediated by a membrane spanning cell surface receptor that has been shown to consist of disulfide-linked 135-kDa and 95-kDa alpha- and beta-subunits that are cleaved products of a common precursor. Binding of INS to the receptor extracellular domain results in intracellular activation of a tyrosine-specific kinase activity and the generation of signals that determine the cellular response . This antibody raised against 980-1382aa of human INS receptor can recognize full-length INS receptor precursor and INS receptor beta subunit.
Images
 | Western blot analysis of INSR (GB113501) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |