| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Ionotropic Glutamate receptor 2 rabbit polyclonal antibody |
Gene Name: | Glutamate receptor 2 |
Synonyms: | GluR-2, AMPA-selective glutamate receptor 2, GluR-B, HBGR2, GluR-K2, Glur2, Glutamate receptor ionotropic, AMPA 2, GluA2, Gria2 |
Immunogen: | Recombinant protein corresponding to Mouse Ionotropic Glutamate receptor 2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membran, Cytoplasm |
Uniprot ID: | P23819, P19491 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 400-1: 2000 | brain |
Background
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse.
Images
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Immunohistochemistry of paraffin embedded mouse brain using GLUR2 (GB111578) at dilution of 1:400 (300x lens) |
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Immunohistochemistry of paraffin embedded rat brain using GLUR2 (GB111578) at dilution of 1:400 (300x lens) |
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Immunofluorescence of paraffin embedded mouse brain using GLUR2 (GB111578) at dilution of 1:1000 (300x lens) |
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Immunofluorescence of paraffin embedded rat brain using GLUR2 (GB111578) at dilution of 1:1000 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |