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| Reactivity: | H,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | C-type lectin domain family 2 member A |
Synonyms: | CLEC2A, INPE5792, PILAR, UNQ5792, Keratinocyte-associated C-type lectin |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human CLEC2A |
Uniprot ID: | Q6UVW9 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Product Usage Information
IHC/IF | Human, Rat | 1: 700-1: 2100 | liver, endometrial carcinoma, gastric carcinoma, esophageal carcinoma |
Background
Plays a role in modulating the extent of T-cell expansion. Enhances the expansion of TCR-stimulated T-cells by increasing their survival through enhanced expression of anti-apoptotic proteins. May modulate the capacity of T-cells to home to lymph nodes through SELL. Facilitates dedicated immune recognition of keratinocytes via interaction with its receptor KLRF2 by stimulating natural killer cell mediated cytotoxicity.
Images
| Immunohistochemistry analysis of paraffin embedded rat liver using CLEC2A (GB115305) at dilution of 1:700 |
| Immunohistochemistry analysis of paraffin embedded human endometrial carcinoma using CLEC2A (GB115305) at dilution of 1:700 |
| Immunohistochemistry analysis of paraffin embedded human gastric carcinoma using CLEC2A (GB115305) at dilution of 1:700 |
| Immunohistochemistry analysis of paraffin embedded human esophageal carcinoma using CLEC2A (GB115305) at dilution of 1:700 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |