| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | CLOCK-interacting pacemaker |
Synonyms: | KIAA1737, CIPC |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse KIAA1737/CIPC |
Uniprot ID: | Q8R0W1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 46 kDa / 50 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 2000-1: 3000 | heart |
Background
Transcriptional repressor which may act as a negative-feedback regulator of CLOCK-ARNTL/BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulate ARNTL/BMAL1-dependent phosphorylation of CLOCK. However, the physiogical relevance of these observations is unsure, since experiments in knockout mice showed that CIPC is not critially required for basic circadian clock.
Images
| Western blot analysis of KIAA1737 (GB115401) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |