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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | LGR5 rabbit polyclonal antibody |
Gene Name: | Leucine-rich repeat-containing G-protein coupled receptor 5 |
Synonyms: | G-protein coupled receptor 49, Orphan G-protein coupled receptor FEX, Lgr5, Gpr49, FEX, HG38 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse LGR5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 100 kDa |
Observed MW. | 130 kDa |
Uniprot ID: | O75473, Q9Z1P4 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | kidney |
Background
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
Images
| Western blot analysis of GPR49 (GB112018) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |