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Anti-LOXL4 Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | LOXL4 rabbit polyclonal antibody |
Gene Name: | Lysyl oxidase homolog 4 |
Synonyms: | Lysyl oxidase-like protein 4, Lysyl oxidase-related protein C, Loxl4, Loxc |
Immunogen: | Recombinant protein corresponding to Mouse LOXL4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | Q96JB6, Q924C6 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse | 1: 400-1: 800 | kidney, placenta |
Background
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Images
| Immunohistochemistry of paraffin embedded human placenta using LOXL4 (GB111854) at dilution of 1:400 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse kidney using LOXL4 (GB111854) at dilution of 1:400 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |