| Reactivity: | M | 
| Applications: | IHC/IF | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Gene Name: | Lymphatic vessel endothelial hyaluronic acid receptor 1  | 
Synonyms:  | CRSBP-1, CRSBP1, HAR, Hyaluronic acid receptor, LYVE-1, LYVE1, XLKD1, Cell surface retention sequence-binding protein 1  | 
Immunogen:  | KLH conjugated Synthetic peptidecorresponding to Mouse LYVE1  | 
Uniprot ID:  | Q8BHC0  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Subcellular location:  | Cell Membrane  | 
Product Usage Information
IHC/IF  | Mouse  | 1: 2000-1: 4000  | small intestine, lymph node  | 
Background
LYVE1 is a 322-amino acid type-I integral membrane glycoprotein primarily expressed on lymphatic endothelial cells. LYVE1 is a CD44 homologue. It acts as a receptor and binds to both soluble and immobilized hyaluronan. LYVE1 may function in lymphatic hyaluronan transport and have a role in tumor metastasis.
Images
  | IHC analysis of lyve-1 (GB113499). Sample: Mouse small intestine (Paraffin), 4% PFA (G1101) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (G1201),98°C,20 min. Blocking buffer: 3% BSA in PBS (GC305010), RT, 30min. Primary antibody: 1: 2000, 4°C overnight. Secondary antibody: HRP Goat Anti-Rabbit lgG (GB23303), 1: 200 RT 1h.  | 
  | IF analysis of C1005 (GB113499). Sample: Mouse lymph node (Paraffin), 4% PFA (G1101) 12-24h. Antigen retrieval: TE buffer (pH 9.0) (G1203),98°C,20min. Blocking buffer: 3% BSA in PBS (GC305010), RT, 30min. Primary antibody: 1: 3600, 4°C overnight. Secondary antibody: Cy3 conjugated Goat Anti-Rabbit IgG (H+L) (GB21303), 1: 300 RT, 1h.  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |