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Anti-M-CSF Receptor Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | M-CSF Receptor rabbit polyclonal |
Gene Name: | Macrophage colony-stimulating factor 1 receptor |
Synonyms: | CSF1R, C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R, Colony stimulating factor 1 receptor, MCSF receptor, M-CSF Receptor |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse M-CSF Receptor |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 500-1: 3000 | splenitis, spleen |
IF | Mouse, Rat | 1: 500-1: 1000 | spleen |
Background
Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein. The encoded protein is a single pass type I membrane protein and acts as the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most of the biological effects of this cytokine. Ligand binding activates CSF1R through a process of oligomerization and trans-phosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse splenitis using M-CSF Receptor (GB11581) at dilution of 1: 500 |
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Immunohistochemistry analysis of paraffin-embedded mouse spleen using M-CSF Receptor (GB11581) at dilution of 1: 500 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse spleen using MCSF (GB11581) at dilution of 1: 500 |
Storage
| Storage |
Store at -20°C for one year. Avoid repeated freeze/thaw cycles |
| Storage Buffer |
PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol. |