| Reactivity: | M,R | 
| Applications: | WB | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Full Name: | MANSC1 rabbit polyclonal  | 
Gene Name:  | MANSC domain-containing protein 1  | 
Synonyms:  | Mansc1, Loss of heterozygosity 12 chromosomal region 3 protein, LOH12CR3  | 
Immunogen:  | Recombinant protein corresponding to Mouse MANSC1  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Predicted MW.  | 45 kDa  | 
Observed MW.  | 62 kDa  | 
Uniprot ID:  | 
Product Usage Information
Applications  | Species  | Dilution  | Positive tissue  | 
WB  | Mouse, Rat  | 1: 1000-1: 2000  | brain  | 
Background
MANSC1 is a 414 amino acid single-pass membrane protein. Expressed throughout the body, MANSC1 contains one MANSC domain and is encoded by a gene that is located on chromosome 12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction.
Images
![]()  | Western blot analysis of MANSC1 (GB112939) at dilution of 1: 1000  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |