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Anti-MCM-BP Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Mini-chromosome maintenance complex-binding protein |
Synonyms: | C10orf119, MCM-BP, MCMBP |
Immunogen: | Recombinant protein corresponding to Mouse MCM-BP |
Uniprot ID: | Q8R3C0 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 73 kDa / 73 kDa |
Product Usage Information
WB | Human | 1: 300- 1: 600 | liver |
Background
Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion (By similarity).
Images
| Western blot analysis of MCMBP (GB114180) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |