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| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MEKK1 rabbit polyclonal antibody |
Gene Name: | Mitogen-activated protein kinase kinase kinase 1 |
Synonyms: | MAP3K1, MAPKKK1, MEKK, MEKK 1, MEKK1, SRXY6, Mitogen-activated protein kinase kinase kinase 1 |
Immunogen: | Recombinant protein corresponding to Mouse MEKK1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 161 kDa |
Observed MW. | 161 kDa |
Uniprot ID: | Q13233, Q62925, P53349 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, colon |
Background
Mitogen-activated protein kinase kinase kinase 1 is an enzyme that in humans is encoded by the MAP3K1 gene. MAP3K, or MEK kinase or Raf, is a serine/threonine kinase that occupies a pivotal role in a network of phosphorylating enzymes integrating cellular responses to a number of mitogenic and metabolic stimuli, including insulin and many growth factors. Mouse genetics has revealed that the kinase is important in: correct embryogenesis, keratinocyte migration, T cell cytokine production and B cell antibody production.
Images
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Western blot analysis of MEKK1 (GB11563) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |