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Anti-Methionine Aminopeptidase 2/p67 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Methionine Aminopeptidase 2/p67 rabbit polyclonal |
Gene Name: | Methionine aminopeptidase 2 |
Synonyms: | MAP 2, MAP2, MetAP 2, METAP2, methionyl aminopeptidase 2, MNPEP, p67, p67eIF2, Peptidase M 2, Initiation factor 2-associated 67 kDa glycoprotein |
Immunogen: | Recombinant protein corresponding to Mouse Methionine Aminopeptidase 2/p67 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 53 kDa |
Observed MW. | 67 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | kidney, testis, spleen |
Background
This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2.
Images
 | Western blot analysis of METAP2 (GB113574) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |