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Anti-MyD88 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MyD88 rabbit polyclonal antibody |
Gene Name: | Myeloid differentiation primary response protein MyD88 |
Synonyms: | MYD88, MYD88D, mutant myeloid differentiation primary response 88, myeloid differentiation primary response gene (88) |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human MyD88 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 33kDa |
Observed MW. | 33kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human,Mouse,Rat | 1: 500-1: 1000 | kidney, liver, lung |
IHC/IF | Human,Mouse,Rat | 1: 1200-1: 2400 | small intestine, lung, pneumonia |
Background
MYD88 is a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. MYD88 is the key adaptor protein for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS, which are essential for innate immunity and pathogen-associated molecular pattern recognition. Mutations in the MyD88 gene lead to the development of cancer in humans and mice suggesting that MyD88 also plays a cell autonomous role in tissue homeostasis.
Images
| Western blot analysis of MyD88 (GB111554) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded human small intestine using MyD88 (GB111554) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin-embedded mouse lung using MyD88 (GB111554) at dilution of 1: 120 |
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Immunohistochemistry analysis of paraffin-embedded rat pneumonia using MyD88 (GB111554) at dilution of 1: 1200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |