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Anti-NC2 alpha Rabbit pAb (100 μl)
| Reactivity: | H,M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Dr1-associated corepressor |
Synonyms: | Dr1 associated corepressor, Dr1 associated protein 1, DRAP1, NC2 alpha, Negative co factor 2 alpha |
Immunogen: | Recombinant protein corresponding to Mouse NC2 alpha |
Uniprot ID: | Q9D6N5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 22 kDa / 27 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500- 1: 1000 | testis, lung, kidney |
IHC/IF | Mouse, Rat | 1: 2000-1: 4000 | testis |
Background
The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity).
Images
| Western blot analysis of DRAP1 (GB114187) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse testis using DRAP1 (GB114187) at dilution of 1: 2000 |
| Immunofluorescence analysis of paraffin embedded mouse testis using DRAP1 (GB114187) at dilution of 1: 4000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |