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Anti-NPY1R Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | NPY1R rabbit polyclonal |
Gene Name: | Neuropeptide Y receptor type 1 |
Synonyms: | NPY1-R, Npy1r, NPYR, NPYY1, Neuropeptide Y receptor Y1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse NPY1R |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 800-1: 1600 | spinal cord |
Background
This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity.
Images
| Immunohistochemistry analysis of paraffin-embedded mouse spinal cord using NPY1R (GB113733) at dilution of 1: 1600 |
| Immunohistochemistry analysis of paraffin-embedded rat spinal cord using NPY1R (GB113733) at dilution of 1: 1600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |